NO-REACT® PATCH

A permanent tissue structure

PORCINE PERICARDIAL PATCH

The BioIntegral Surgical No-React® treated pericardial patches are highly durable, easy to handle without the need of pre-operative rinsing. Available in various sizes.

No-React® treated tissue has been shown to resist infection while preserving cellular and connective tissue structures. It is highly resistant to adhesions, even in pediatrics

THE NO-REACT® TREATMENT

BioIntegral Surgical uses the No-React® treatment. No-React is a proprietary detoxification of glutaraldehyde-treated tissue.

17 years of clinical experience with No-React® shows:

  • reduced toxicity, enhanced biocompatiblity

  • No dilatation due to effective No-React® treatment

  • lower rates of infection, adhesion and calcification

  • the promotion of endothelial lining

THE PERICARDIAL PATCH

  • Exceptional long term resilience and durability

  • Demonstrated 100% biocompatability and low cytotoxicity

  • Extremely low rate of infection and thrombogenicity

  • Total mitigation of calcification, regardless of age

  • Excellent suture reapproximation, reduced need for hemostatic agents

  • High tensile and pull strength, uniform suture retention

  • More than 300,000 implants

Elevated levels of anti-HLA antibodies is correlated to early acute and chronic rejections and worsen pediatric cardiac transplantations. the No-React treated patches do not produce anti-HLA antibodies and are excellent candidates for pediatric surgery, cardiac surgery, and vascular surgery

NO ANTI-HLA BODIES

  • Intracardiac patch to close intercavity defects

  • Enlargement of aortic root

  • Carotid endarterectomy

  • Pericardial closure

  • Soft tissue repair

CONTRAINDICATIONS

  • Patients with active sternal infections

  • As pericardial closures in immunosuppressed patients

INDICATIONS